Phenotypes Associated with This Genotype

Genotype
MGI:5788090

• Allelic Composition: Aqp5^{tm1.1(cre)Pfl}/?; Atp1b1^tm1.1Zboro/Atp1b1^tm1.1Zboro
• Genetic Background: 129S-Atp1b1^tm1.1Zboro Aqp5^{tm1.1(cre)Pfl}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

impaired pulmonary alveolar fluid clearance ( J:233742 )

• 43% reduction in alveolar fluid clearance as compared to controls

respiratory system

respiratory system phenotype ( J:233742 )

N • lung permeability, wet-to-dry lung weight rations and lung morphology are similar to controls

impaired pulmonary alveolar fluid clearance ( J:233742 )

• 43% reduction in alveolar fluid clearance as compared to controls