Analysis Tools
mortality/aging
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• all mice die rapidly within 5 to 30 minutes after Caesarean section
|
|
• fewer than expected mice are present at E16.5
• however, many mice are still alive at E18.5
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craniofacial
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• disturbed secondary palate shelf formation in the upper jaw
|
|
• invagination-like elevated cartilage structures along the lateral hard palate fusion line in the anterior direction
|
|
• at E16.5 and E18.5
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respiratory system
| N |
• mice exhibit normal lung weight, diaphragm, gasping movement and costal retraction
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• mice do not initiate breathing at birth
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behavior/neurological
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• newborn mice fail to emit sounds upon soft pressure on their tail unlike wild-type mice
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homeostasis/metabolism
integument
skeleton
| N |
• mice exhibit normal bone mineralization and ossification in areas outside of the upper jaw
|
|
• in the secondary palate shelf fusion area
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digestive/alimentary system
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• disturbed secondary palate shelf formation in the upper jaw
|
|
• invagination-like elevated cartilage structures along the lateral hard palate fusion line in the anterior direction
|
|
• at E16.5 and E18.5
|
growth/size/body
|
• disturbed secondary palate shelf formation in the upper jaw
|
|
• invagination-like elevated cartilage structures along the lateral hard palate fusion line in the anterior direction
|
|
• at E16.5 and E18.5
|
