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Phenotypes Associated with This Genotype
Genotype
MGI:5784674
Allelic
Composition		 Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129S6/SvEvTac * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan mutation (2 available); any Gt(ROSA)26Sor mutation (1098 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal ovary morphology ( J:219794 )
• mice injected intrabursally with an adenovirus expressing cre recombinase (AdCre) exhibit multifocal sites of epithelial hyperplasia in the ovarian surface epithelium

neoplasm
neoplasm ( J:219794 )
N
• however, intrabursally AdCre injected mice do not form ovarian tumors

reproductive system
abnormal ovary morphology ( J:219794 )
• mice injected intrabursally with an adenovirus expressing cre recombinase (AdCre) exhibit multifocal sites of epithelial hyperplasia in the ovarian surface epithelium

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory