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Phenotypes Associated with This Genotype
Genotype
MGI:5781124
Allelic
Composition		 Baxtm1Sjk/Baxtm1Sjk
Col25a1tm1.1Tiwa/Col25a1tm1.1Tiwa
Genetic
Background		 B6.Cg-Col25a1tm1.1Tiwa Baxtm1Sjk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baxtm1Sjk mutation (1 available); any Bax mutation (24 available)
Col25a1tm1.1Tiwa mutation (0 available); any Col25a1 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal phrenic nerve innervation pattern to diaphragm ( J:206855 )
• at E14.5, motor neuron projections reach the diaphragm but fail to innervate the muscle fibers unlike in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory