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Phenotypes Associated with This Genotype
Genotype
MGI:5779955
Allelic
Composition		 Rack1tm1Sbif/Rack1tm1Sbif
Genetic
Background		 C57BL/6-Rack1tm1Sbif
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rack1tm1Sbif mutation (1 available); any Rack1 mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and placentation, complete penetrance ( J:223207 )
• homozygotes die at gastrulation; mutant embryos are resorbed at E9.5

embryo
abnormal embryo development ( J:223207 )
• disorganized implanted blastocysts with vacuolar areas are observed at E6.5
absent egg cylinders ( J:223207 )
• absence of the early egg cylinder at E6.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory