Phenotypes Associated with This Genotype

Genotype
MGI:5776357

• Allelic Composition: Smg9^em1(IMPC)J/Smg9^em1(IMPC)J
• Genetic Background: involves: C57BL/6NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:231968 )

• no pups are produced from breeding heterozygous mice

lethality throughout fetal growth and development, incomplete penetrance ( J:231968 )

cardiovascular system

thin myocardium ( J:231968 )

atrioventricular septal defect ( J:231968 )

hemorrhage ( J:231968 )

• variable with incompletely penetrance at E15.5

• in two mice at E18.5

nervous system

decreased hindbrain size ( J:231968 )

decreased midbrain size ( J:231968 )

exencephaly ( J:231968 )

• variable with incompletely penetrance at E15.5

growth/size/body

decreased fetal size ( J:231968 )

fetal growth retardation ( J:231968 )

vision/eye

microphthalmia ( J:231968 )

homeostasis/metabolism

edema ( J:231968 )

• variable with incompletely penetrance at E15.5

• variable in two mice at E18.5

limbs/digits/tail

preaxial polydactyly ( J:231968 )

muscle

thin myocardium ( J:231968 )