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Phenotypes Associated with This Genotype
Genotype
MGI:5775443
Allelic
Composition		 Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Pax3Sp-d/Pax3Sp-d
Tg(Prrx1-cre)1Cjt/0
Genetic
Background		 involves: 129S4/SvJaeSor * C57BL/6J * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1Sor mutation (10 available); any Gt(ROSA)26Sor mutation (1098 available)
Pax3Sp-d mutation (1 available); any Pax3 mutation (50 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal diaphragm morphology ( J:231793 )
• muscleless diaphragms
• however, pleuroperitoneal fold-derived muscle connective tissue is present and mice do not develop diaphragmatic hernias

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory