Phenotypes Associated with This Genotype

Genotype
MGI:5774649

• Allelic Composition: Sufu^rgsc2062/Sufu^rgsc2062
• Genetic Background: either: B6JJcl(C3JJcl)-Sufu^rgsc2062 or B6JJcl(D2JJcl)-Sufu^rgsc2062

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:228335 )

• mice die between E14 and E18

limbs/digits/tail

abnormal limb morphology ( J:228335 )

polydactyly ( J:228335 )

• severe with unpatterned digits

nervous system

exencephaly ( J:228335 )

cardiovascular system

hemorrhage ( J:228335 )

craniofacial

abnormal craniofacial morphology ( J:228335 )

respiratory system

small lung ( J:228335 )

• small and thickened

• however, the number of lobes is correct

homeostasis/metabolism

edema ( J:228335 )

• peripheral edema