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Phenotypes Associated with This Genotype
Genotype
MGI:5774472
Allelic
Composition
Gt(ROSA)26Sortm1(en/Cdx1,-EGFP)Npln/Gt(ROSA)26Sor+
Pax3Sp/Pax3+
Tg(Pax3-cre)1Joe/0
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(en/Cdx1,-EGFP)Npln mutation (0 available); any Gt(ROSA)26Sor mutation (1095 available)
Pax3Sp mutation (4 available); any Pax3 mutation (50 available)
Tg(Pax3-cre)1Joe mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• posterior pigmentation anomalies of each single mutant are accentuated in all double mutants
• lack of pigmentation in the forepaws and hindpaws
• lack of pigmentation in the distal tail

nervous system
• mice exhibit hypoganglionosis

pigmentation
• posterior pigmentation anomalies of each single mutant are accentuated in all double mutants
• lack of pigmentation in the forepaws and hindpaws
• lack of pigmentation in the distal tail


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory