cellular
• melanoblasts migrating along the dorsolateral pathway in hindlimb buds are not well aligned in mutants
|
embryo
• melanoblasts migrating along the dorsolateral pathway in hindlimb buds are not well aligned in mutants
|
integument
• increase in penetrance and extent of white spotting in the posterior regions
|
belly spot
(
J:231654
)
nervous system
• E10.5 mutants exhibit abnormalities of the hypoglossal nerve, with the converging roots appearing disorganized and less dense and resulting in a reduced number of elongating axons that are shorter
|
• E10.5 embryos exhibit the presence of fusions of dorsal root ganglia in the cervical region
|
pigmentation
• increase in penetrance and extent of white spotting in the posterior regions
|
belly spot
(
J:231654
)