Analysis Tools
mortality/aging
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• a high number of newborns die at about P1, with very little, if any, milk in their stomach
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• a subset of mutants with severe growth delay die at around P10
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behavior/neurological
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• newborns that die at P1 have very little, if any, milk in their stomachs
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growth/size/body
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• mutants that survive past P2 exhibit severe growth delay
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integument
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• 100% of mice that survive past P2 show pigmentation anomalies
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• mice that survive past P2 lack pigmentation in the hindpaws
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• mice that survive past P2 lack pigmentation in the distal tail
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belly spot
(
J:231654
)
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• in about 25% of surviving mice, a tiny white spot is seen on the belly
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limbs/digits/tail
kinked tail
(
J:231654
)
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• half of newborns exhibit a kinked tail
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pigmentation
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• 100% of mice that survive past P2 show pigmentation anomalies
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• mice that survive past P2 lack pigmentation in the hindpaws
|
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• mice that survive past P2 lack pigmentation in the distal tail
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belly spot
(
J:231654
)
|
• in about 25% of surviving mice, a tiny white spot is seen on the belly
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renal/urinary system
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• about half of mice that die at P10 exhibit hydronephrotic kidney
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reproductive system
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• mice exhibit reproduction problems
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