Phenotypes for Tg(Tcra2D2,Tcrb2D2)1Kuch Vsir MGI:5770298 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Vsir^tm1Lex/Vsir^tm1Lex Tg(Tcra2D2,Tcrb2D2)1Kuch/0
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Tcra2D2,Tcrb2D2)1Kuch mutation (2 available)
Vsir^tm1Lex mutation (2 available); any Vsir mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased susceptibility to experimental autoimmune encephalomyelitis ( J:222944 )

• mice exhibit accelerated onset compared with control mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24