Phenotypes for Cftr MGI:5766743 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cftr^tm1Hsc/Cftr^tm1Hsc
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cftr^tm1Hsc mutation (0 available); any Cftr mutation (97 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:31759 )

• Background Sensitivity: most homozygotes survive to 20 days of age with the majority dying between 20 and 35 days of age (class II mice); 25% survive longer than 6 weeks of age (class III mice)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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