Phenotypes Associated with This Genotype

Genotype
MGI:5763069

• Allelic Composition: Supt4a^tm1Yty/Supt4a⁺; Tg(HDexon1)62Gpb/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:224237 )

• mice exhibit premature death compared with wild-type mice but improved survival compared with Tg(HDexon1)62Gpb mice

behavior/neurological

impaired coordination ( J:224237 )

• impaired performance on a rotarod is delayed until 13 weeks of age compared with 10 weeks as in Tg(HDexon1)62Gpb mice

• improved beam walking compared with Tg(HDexon1)62Gpb mice

growth/size/body

decreased body weight ( J:224237 )

• as in Tg(HDexon1)62Gpb mice