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Phenotypes Associated with This Genotype
Genotype
MGI:5755251
Allelic
Composition		 Tg(Myh6-Tnnt2*R92Q)1Lnwd/0
Genetic
Background		 involves: C57BL/6
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No mouse lines available in IMSR.
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal heart atrium morphology ( J:56911 )
• progressive atrial hypertrophy
cardiac hypertrophy ( J:56911 )
• progressive atrial hypertrophy
• hearts exhibit expression of hypertrophic markers
abnormal heart ventricle morphology ( J:56911 )
• ventricular mass decreases by about 18%

muscle
abnormal sarcomere morphology ( J:56911 )
• sarcomere lengths are shorter in left ventricular myocytes

growth/size/body
cardiac hypertrophy ( J:56911 )
• progressive atrial hypertrophy
• hearts exhibit expression of hypertrophic markers

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory