Phenotypes Associated with This Genotype

Genotype
MGI:5754733

• Allelic Composition: Myf5^tm3(cre)Sor/Myf5⁺; Tg(ACTB-Edn1)1416Clou/0
• Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

upper jaw to lower jaw transformation ( J:221133 )

• one mutant exhibits partial homeotic transformation of the maxilla into a mandible

skeleton

upper jaw to lower jaw transformation ( J:221133 )

• one mutant exhibits partial homeotic transformation of the maxilla into a mandible

abnormal costal cartilage morphology ( J:221133 )

• fusions between the first and second costal cartilages, with varying other costal cartilage fusions at E18.5

rib fusion ( J:221133 )

• fusions between adjoining ribs

growth/size/body

upper jaw to lower jaw transformation ( J:221133 )

• one mutant exhibits partial homeotic transformation of the maxilla into a mandible