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Phenotypes Associated with This Genotype
Genotype
MGI:5705505
Allelic
Composition		 Kdrtm2Sato/Kdrtm2Sato
Vegfatm2Gne/Vegfatm2Gne
Tg(Pax6-cre,GFP)2Pgr/0
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdrtm2Sato mutation (1 available); any Kdr mutation (67 available)
Tg(Pax6-cre,GFP)2Pgr mutation (0 available)
Vegfatm2Gne mutation (2 available); any Vegfa mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal retina vasculature morphology ( J:217533 )
• some arteriovenous crossings is observed
• however, mice do not exhibit early vertical vascular branching in the retina observed in Kdrtm2.1Jrt/Kdrtm2.1Jrt Tg(Pax6-cre,GFP)2Pgr mice

vision/eye
abnormal retina vasculature morphology ( J:217533 )
• some arteriovenous crossings is observed
• however, mice do not exhibit early vertical vascular branching in the retina observed in Kdrtm2.1Jrt/Kdrtm2.1Jrt Tg(Pax6-cre,GFP)2Pgr mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory