About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5705502
Allelic
Composition		 Dnm1tm2.1Pdc/Dnm1tm2.1Pdc
Dnm2tm1.1Pdc/Dnm2tm1.1Pdc
Tg(Pax6-cre,GFP)2Pgr/0
Genetic
Background		 involves: 129S1/SvImJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnm1tm2.1Pdc mutation (1 available); any Dnm1 mutation (40 available)
Dnm2tm1.1Pdc mutation (1 available); any Dnm2 mutation (101 available)
Tg(Pax6-cre,GFP)2Pgr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal retina vasculature morphology ( J:217533 )
• superficial plexus is more severely impaired than in Kdrtm2.1Jrt/Kdrtm2.1Jrt Tg(Pax6-cre,GFP)2Pgr mice

vision/eye
abnormal retina vasculature morphology ( J:217533 )
• superficial plexus is more severely impaired than in Kdrtm2.1Jrt/Kdrtm2.1Jrt Tg(Pax6-cre,GFP)2Pgr mice
abnormal retina neuronal layer morphology ( J:217533 )
• insufficient separation of the inner and outer nuclear layers with fewer Pax6+ cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory