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Phenotypes Associated with This Genotype
Genotype
MGI:5703836
Allelic
Composition		 Syne1tm1Chen/Syne1tm1Chen
Tg(Nkx2-5-cre)9Eno/?
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * Black Swiss
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Syne1tm1Chen mutation (0 available); any Syne1 mutation (201 available)
Tg(Nkx2-5-cre)9Eno mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell nucleus morphology ( J:211007 )
• nuclei are less circular
• nuclei are closer together in binuclear cardiomyocytes
abnormal cell nucleus size ( J:211007 )
• nuclei are enlarged

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory