Phenotypes Associated with This Genotype

Genotype
MGI:5702889

• Allelic Composition: Gt(ROSA)26Sor^{tm1(GNAQ*)Cvrk}/Gt(ROSA)26Sor⁺; Tg(Tyr-cre/ERT2)13Bos/0
• Genetic Background: C3FeJ.Cg-Tg(Tyr-cre/ERT2)13Bos Gt(ROSA)26Sor^{tm1(GNAQ*)Cvrk}/Cvrk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal melanocyte morphology ( J:225597 )

• melanocytic hyperplasia in tamoxifen treated mice after 2 and 6.5 months

hyperpigmentation ( J:225597 )

• 2 months after tamoxifen treatment

vision/eye

exophthalmos ( J:225597 )

• 2 months after tamoxifen treatment

behavior/neurological

behavior/neurological phenotype ( J:225597 )

N • tamoxifen-treated mice do not exhibit any behavioral abnormalities

neoplasm

neoplasm ( J:225597 )

N • tamoxifen-treated mice fail to develop uveal melanoma