Phenotypes for Mapt Runx1 MGI:5702485 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mapt^tm2Arbr/? Runx1^tm3Spe/Runx1^{tm1(cre/Esr1*)Ims}
Genetic Background	involves: 129S4/SvJae * C57BL/6NCrlj * CBA/JNCrlj

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapt^tm2Arbr mutation (1 available); any Mapt mutation (453 available)
Runx1^{tm1(cre/Esr1*)Ims} mutation (0 available); any Runx1 mutation (34 available)
Runx1^tm3Spe mutation (0 available); any Runx1 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal mechanoreceptor morphology ( J:226826 )

• few or no tyrosine hydroxylase C-low threshold mechanoreceptors (C-LTMRs) are observed in P21 mice following tamoxifen administration at P2

• decrease in the number of longitudinal lanceolate endings (characteristic of C-LTMRs) in back hairy skin of P21 mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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