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Phenotypes Associated with This Genotype
Genotype
MGI:5702484
Allelic
Composition		 Cbfbtm2.1Ddg/Cbfbtm2.1Ddg
Mapttm2Arbr/?
Runx1tm1(cre/Esr1*)Ims/?
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NCrlj * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cbfbtm2.1Ddg mutation (1 available); any Cbfb mutation (36 available)
Mapttm2Arbr mutation (1 available); any Mapt mutation (428 available)
Runx1tm1(cre/Esr1*)Ims mutation (0 available); any Runx1 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal mechanoreceptor morphology ( J:226826 )
• few or no tyrosine hydroxylase C-low threshold mechanoreceptors (C-LTMRs) are observed in P21 mice following tamoxifen administration at P2
• decrease in the number of longitudinal lanceolate endings (characteristic of C-LTMRs) in back hairy skin of P21 mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory