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Phenotypes Associated with This Genotype
Genotype
MGI:5702313
Allelic
Composition		 Cd160tm1Yxf/Cd160tm1Yxf
Genetic
Background		 C57BL/6-Cd160tm1Yxf
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd160tm1Yxf mutation (1 available); any Cd160 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased interferon-gamma secretion ( J:222131 )
• reduced interferon gamma production from splenocytes stimulated by Nk1.1 cross-linking

neoplasm
increased tumor growth/size ( J:222131 )
• increased tumor volume following inoculation with NK-dependent B16 tumor cells as compared to inoculated wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory