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Phenotypes Associated with This Genotype
Genotype
MGI:5701642
Allelic
Composition		 Myd88tm1Aki/Myd88tm1Aki
Sh3bp2tm1.1Ics/Sh3bp2tm1.1Ics
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myd88tm1Aki mutation (9 available); any Myd88 mutation (50 available)
Sh3bp2tm1.1Ics mutation (0 available); any Sh3bp2 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:221901 )
N
• serum TNF-alpha levels are similar to wild-type levels

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory