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Phenotypes Associated with This Genotype
Genotype
MGI:5699095
Allelic
Composition		 Apoetm1Unc/Apoetm1Unc
Tg(EIF1AX-Aldh2*E487K)101Oht/Tg(EIF1AX-Aldh2*E487K)101Oht
Genetic
Background		 B6.Cg-Apoetm1Unc Tg(EIF1AX-Aldh2*E487K)101Oht
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1Unc mutation (34 available); any Apoe mutation (163 available)
Tg(EIF1AX-Aldh2*E487K)101Oht mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired spatial learning ( J:137374 )
• 6 month old mutants are unable to learn the Morris water maze task and the time spent in the target quadrant during probe trials is shorter than in either single mutant

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory