Phenotypes Associated with This Genotype

Genotype
MGI:5696783

• Allelic Composition: Arid5b^tm1Whit/Arid5b^tm1Whit
• Genetic Background: B6.129S1-Arid5b^tm1Whit

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:223502 )

• dwarf phenotype observed at 3 weeks of age

• some level of dwarfing noticeable at 1 day of age as well

• slight dwarfing at E14.5

skeleton

short tibia ( J:223502 )

• shortened tibia at 1 day of age

abnormal long bone epiphyseal plate morphology ( J:223502 )

• marked reduction in the Col2 positive area of the tibial growth plate at 3 weeks of age

abnormal long bone hypertrophic chondrocyte zone ( J:223502 )

• Col10 positive hypertrophic zone is absent in E14.5 embryos

abnormal endochondral bone ossification ( J:223502 )

• marginal impairment of endochondral ossification

limbs/digits/tail

short tibia ( J:223502 )

• shortened tibia at 1 day of age