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Phenotypes Associated with This Genotype
Genotype
MGI:5696325
Allelic
Composition		 Gipc1tm1.1Mhsi/Gipc1tm1.1Mhsi
Tg(Myh11-cre,-EGFP)2Mik/?
Genetic
Background		 involves: 129S1/SvImJ * 129S4/SvJaeSor * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gipc1tm1.1Mhsi mutation (1 available); any Gipc1 mutation (42 available)
Tg(Myh11-cre,-EGFP)2Mik mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:221554 )
N
• normal arterial tree branching and collateral artery number in the heart and kidney
• normal spinotrapezius arterial tree
• blood flow recovery after hindlimb ischemia is similar to controls at 2 weeks
abnormal systemic artery morphology ( J:221554 )
• trend toward fewer small arteries in heart and kidney
• trend toward larger arterial size in hind limbs

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory