Phenotypes Associated with This Genotype

Genotype
MGI:5694212

• Allelic Composition: Ctnnb1^tm2Kem/Ctnnb1^tm2Kem; Gt(ROSA)26Sor^tm1(Fgf8)Lma/Gt(ROSA)26Sor⁺; Tg(Msx2-cre)5Rem/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:223057 )

N • unlike in mice lacking Fgf8 over-expression, mice develop normal humeri with deltoid tuberosity and the radius is evident

abnormal autopod morphology ( J:223057 )

• autopod rudiments

abnormal ulna morphology ( J:223057 )

• the ulna is longer and thicker

abnormal hindlimb morphology ( J:223057 )

• near normal pelvic girdles and femurs with one or two ectopic cartilages

skeleton

abnormal ulna morphology ( J:223057 )

• the ulna is longer and thicker