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Phenotypes Associated with This Genotype
Genotype
MGI:5694057
Allelic
Composition
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-DRD3)3-10Kndl/0
Genetic
Background
involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Camk2a-tTA)1Mmay mutation (8 available)
Tg(tetO-DRD3)3-10Kndl mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• reduced number of total lever presses in progressive ratio (PR) measure of incentive motivation
• mice exhibit less motivation to obtain food reward


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory