Phenotypes for Sumo2 Sumo3 MGI:5690075 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Sumo2^tm1Weiy/Sumo2⁺ Sumo3^tm1Weiy/Sumo3^tm1Weiy
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sumo2^tm1Weiy mutation (1 available); any Sumo2 mutation (15 available)
Sumo3^tm1Weiy mutation (1 available); any Sumo3 mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality throughout fetal growth and development, incomplete penetrance ( J:217019 )

• only 2 mutant mice are found at birth in 35 litters after crossing mice that are double heterozygous for Sumo2^tm1Weiy and Sumo3^tm1Weiy with Sumo3^tm1Weiy homozygotes

growth/size/body

decreased birth body size ( J:217019 )

• although mutant mice show no overt phenotype at E15.5 and E17.5, they are considerably smaller than Sumo3^tm1Weiy homozygotes at birth (E19.5)

decreased body size ( J:217019 )

• at P10, mutant mice are significantly smaller than Sumo3^tm1Weiy homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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