About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5688680
Allelic
Composition		 Ntrk1tm1.1Jcar/Ntrk1tm1.1Jcar
Genetic
Background		 involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntrk1tm1.1Jcar mutation (0 available); any Ntrk1 mutation (59 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:219326 )
N
• mice are viable and fertile with a normal life span

nervous system
abnormal sensory neuron physiology ( J:219326 )
• in culture, DRG neurons obtained from E13.5 mutant embryos exhibit enhanced NGF-mediated signaling and increased cell survival in limiting amounts of NGF relative to wild-type neurons

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory