Analysis Tools
growth/size/body
weight loss
(
J:219136
)
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• mice show a decrease in body weight from 16 to 24 weeks of age, however weight loss is less than seen in single transgenic Tg(SFTPC-Il18)AThos mice
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respiratory system
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• mean alveolar chord lengths of 14 week old mice is shorter than in single transgenic mice
• however, pulmonary inflammation and emphysematous changes are not seen in the lungs
enlarged alveolar macrophages and exudates are not present in the lungs
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muscle
|
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• decrease in quadriceps femoris muscle weight at 7 and 16 weeks of age, although muscle is heavier than in single transgenic Tg(SFTPC-Il18)AThos mice and by 25 weeks of age, weight is similar to wild-type mice
• mice show a decrease in gastrocnemius muscle weight at 7 weeks of age but not 16 and 25 weeks of age
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skeleton
|
N |
• bone mineral density is normal
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