Phenotypes Associated with This Genotype

Genotype
MGI:5688364

• Allelic Composition: Vgf^{tm2(VGF*)Srjs}/Vgf^{tm2(VGF*)Srjs}
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:212045 )

N • homozygotes exhibit normalized SBP, DBP and MAP relative to mice homozygous for the Vgf^tm1Vlcg allele, indicating rescue of the hypertensive knockout phenotype

N • notably, homozygotes exhibit a small but significant increase in SBP relative to mice homozygous for the Vgf^tm1(VGF)Srjs allele