Phenotypes Associated with This Genotype

Genotype
MGI:5662416

• Allelic Composition: Mirc1^tm2.1Aven/Mirc1^tm2.1Aven; Tg(ARR2/Pbsn-MYC)7Key/0
• Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

small prostate gland ( J:223213 )

• prostate volume is reduced compared to Tg(ARR2/Pbsn-MYC)7Key alone

decreased prostate gland tumor incidence ( J:223213 )

• prostrates from 8 week old males exhibit occasional prostatic intraepithelial neoplasia in contrast to Tg(ARR2/Pbsn-MYC)7Key alone

increased prostate gland adenocarcinoma incidence ( J:223213 )

• invasive prostatic adenocarcinoma is not observed until 14 months of age in contrast to Tg(ARR2/Pbsn-MYC)7Key alone

reproductive system

small prostate gland ( J:223213 )

• prostate volume is reduced compared to Tg(ARR2/Pbsn-MYC)7Key alone

increased prostate gland adenocarcinoma incidence ( J:223213 )

• invasive prostatic adenocarcinoma is not observed until 14 months of age in contrast to Tg(ARR2/Pbsn-MYC)7Key alone

neoplasm

decreased prostate gland tumor incidence ( J:223213 )

• prostrates from 8 week old males exhibit occasional prostatic intraepithelial neoplasia in contrast to Tg(ARR2/Pbsn-MYC)7Key alone

increased prostate gland adenocarcinoma incidence ( J:223213 )

• invasive prostatic adenocarcinoma is not observed until 14 months of age in contrast to Tg(ARR2/Pbsn-MYC)7Key alone