Phenotypes Associated with This Genotype

Genotype
MGI:5662399

• Allelic Composition: Mirc1^tm4.1Aven/Mirc1^tm4.1Aven
• Genetic Background: B6.Cg-Mirc1^tm4.1Aven

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

cleft palate ( J:223213 )

digestive/alimentary system

cleft palate ( J:223213 )

growth/size/body

cleft palate ( J:223213 )

limbs/digits/tail

fused carpal bones ( J:223213 )

• all mice exhibit fusion of the proximal carpal bones

abnormal phalanx morphology ( J:223213 )

• the fifth mesophalanx of the forelimb is absent in E18.5 embryos

mortality/aging

perinatal lethality, complete penetrance ( J:223213 )

skeleton

fused carpal bones ( J:223213 )

• all mice exhibit fusion of the proximal carpal bones

abnormal phalanx morphology ( J:223213 )

• the fifth mesophalanx of the forelimb is absent in E18.5 embryos

thoracic vertebral transformation ( J:223213 )

• all mice exhibit transformation of vertebra 14 (T7 to T8)

• all mice exhibit transformation of vertebra 20 (T13 to L1a)

lumbar vertebral transformation ( J:223213 )

• all mice exhibit transformation of vertebra 26 (L6 to S1)

vertebral fusion ( J:223213 )

• all mice exhibit vertebral fusion

delayed bone ossification ( J:223213 )