About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5661492
Allelic
Composition
Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0
Tg(Nr4a1-EGFP/cre)820Khog/0
Genetic
Background
involves: C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt mutation (0 available)
Tg(Nr4a1-EGFP/cre)820Khog mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice exhibit a defect in thymocyte negative selection, showing an increase in the proportion of post-selection DP thymocytes which indicates rescue of these cells from death
• mice exhibit a defect in thymocyte negative selection, showing an increase in the proportion of post-selection DP thymocytes which indicates rescue of these cells from death/clonal deletion

hematopoietic system
• mice exhibit a defect in thymocyte negative selection, showing an increase in the proportion of post-selection DP thymocytes which indicates rescue of these cells from death
• mice exhibit a defect in thymocyte negative selection, showing an increase in the proportion of post-selection DP thymocytes which indicates rescue of these cells from death/clonal deletion

endocrine/exocrine glands
• mice exhibit a defect in thymocyte negative selection, showing an increase in the proportion of post-selection DP thymocytes which indicates rescue of these cells from death

cellular
• mice exhibit a defect in thymocyte negative selection, showing an increase in the proportion of post-selection DP thymocytes which indicates rescue of these cells from death


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory