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Phenotypes Associated with This Genotype
Genotype
MGI:5660395
Allelic
Composition		 Efnb3lltw/Efnb3lltw
Genetic
Background		 involves: C3H/HeSnJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb3lltw mutation (1 available); any Efnb3 mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
ataxia ( J:223790 )
• homozygotes on this segregating background also have a severe leaning gait

mortality/aging
prenatal lethality, incomplete penetrance ( J:223790 )
• In this F2 mapping cross only 11 of 157 offspring from heterozygotes (7%) display the ataxic phenotype indicative of prenatal lethality

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory