Phenotypes Associated with This Genotype

Genotype
MGI:5648868

• Allelic Composition: b2b3260Clo/b2b3260Clo
• Genetic Background: C57BL/6J-b2b3260Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 3260-006-2 (E16.5) exhibited an abnormal arrangement of the outflow tracts which was diagnosed as DORV (TOF Type), hypoplastic pulmonary, long right PDA, right aortic arch, and aberrant left subclavian artery by episcopic confocal histopathology

digestive/alimentary system

cleft palate ( J:175213 )

endocrine/exocrine glands

abnormal thymus morphology ( J:175213 )

thymus hypoplasia ( J:175213 )

cardiovascular system

abnormal myocardium compact layer morphology ( J:175213 )

persistent truncus arteriosus ( J:175213 )

transposition of great arteries ( J:175213 )

atrioventricular septal defect ( J:175213 )

abnormal semilunar valve morphology ( J:175213 )

hematopoietic system

abnormal thymus morphology ( J:175213 )

thymus hypoplasia ( J:175213 )

immune system

abnormal thymus morphology ( J:175213 )

thymus hypoplasia ( J:175213 )

renal/urinary system

abnormal kidney morphology ( J:175213 )

kidney cyst ( J:175213 )

limbs/digits/tail

preaxial polydactyly ( J:175213 )

nervous system

exencephaly ( J:175213 )

craniofacial

cleft palate ( J:175213 )

short snout ( J:175213 )

growth/size/body

cleft palate ( J:175213 )

short snout ( J:175213 )

kidney cyst ( J:175213 )

muscle

abnormal myocardium compact layer morphology ( J:175213 )