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Phenotypes Associated with This Genotype
Genotype
MGI:5646623
Allelic
Composition
Tg(Camk2a-MAPT*P301L)D35Jiri/0
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• neurofibrillary tangles start to appear in the cortex of some mice at 4 months, by 8 months they are seen in the hippocampus and cortex of all mice, and by 18 months, they are present in almost all neurons in these regions

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
frontotemporal dementia DOID:9255 OMIM:600274
J:222897


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory