Phenotypes for Atp13a2 Snca MGI:5642336 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Atp13a2^tm1.2Wtd/Atp13a2^tm1.2Wtd Snca^tm1Wtd/Snca^tm1Wtd
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp13a2^tm1.2Wtd mutation (0 available); any Atp13a2 mutation (59 available)
Snca^tm1Wtd mutation (0 available); any Snca mutation (44 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

gliosis ( J:221680 )

• mice show increase in the extent of gliosis compared to single Atp13a2 homozygotes

abnormal lysosome morphology ( J:221680 )

• mice show a similar level of lysosomal accumulation as seen in single Atp13a2 homozygotes

nervous system

gliosis ( J:221680 )

• mice show increase in the extent of gliosis compared to single Atp13a2 homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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