Phenotypes Associated with This Genotype

Genotype
MGI:5633988

• Allelic Composition: Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp/0; Tg(Pbsn-Lrp5/Fkbp1a,-luc*)#Dmps/0
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased prostate gland adenocarcinoma incidence ( J:206727 )

♂ • mice develop adenocarcinoma by 24 weeks after treatment with a chemical inducer of dimerization, AP20187

♂ • however, tumors do not progress until 60 weeks of AP20187 treatment

reproductive system

increased prostate gland adenocarcinoma incidence ( J:206727 )

♂ • mice develop adenocarcinoma by 24 weeks after treatment with a chemical inducer of dimerization, AP20187

♂ • however, tumors do not progress until 60 weeks of AP20187 treatment

endocrine/exocrine glands

increased prostate gland adenocarcinoma incidence ( J:206727 )

♂ • mice develop adenocarcinoma by 24 weeks after treatment with a chemical inducer of dimerization, AP20187

♂ • however, tumors do not progress until 60 weeks of AP20187 treatment