Phenotypes Associated with This Genotype

Genotype
MGI:5631259

• Allelic Composition: L3mbtl2^{tm2a(EUCOMM)Wtsi}/L3mbtl2^{tm2a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-L3mbtl2^{tm2a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0960_5_A06

Data Sources

IMPC Data for L3mbtl2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal trophoblast layer morphology ( J:261316 )

• small or absent trophoblast compartment at E9.5

• biased differentiation (diploid/polyploid trophoblast)

mortality/aging

embryonic lethality during organogenesis, incomplete penetrance ( J:261316 )

• fewer than the expected numbers of embryos are obtained at E9.5

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

lethality throughout fetal growth and development, complete penetrance ( J:261316 )

• complete lethality at E14.5