Phenotypes Associated with This Genotype

Genotype
MGI:5630892

• Allelic Composition: B9d2^{tm1a(EUCOMM)Wtsi}/B9d2^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-B9d2^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0481_2_D09

Data Sources

IMPC Data for B9d2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

persistent right dorsal aorta ( J:239583 )

DMDD

persistent right 6th pharyngeal arch artery ( J:239583 )

DMDD

aortic arch coarctation ( J:239583 )

DMDD

abnormal subclavian artery origin ( J:239583 )

DMDD

abnormal vertebral artery morphology ( J:239583 )

DMDD

abnormal vertebral artery topology ( J:239583 )

DMDD

additional anastomosis between intracranial vertebral arteries ( J:239583 )

DMDD

inverse situs of great intrathoracic arteries ( J:239583 )

DMDD

abnormal brain vasculature morphology ( J:239583 )

DMDD

anastomosis between internal carotid artery and basilar artery ( J:239583 )

DMDD

absent segment of anterior cerebral artery ( J:239583 )

DMDD

absent segment of posterior cerebral artery ( J:239583 )

DMDD

abnormal umbilical vein topology ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

symmetric azygos veins ( J:239583 )

DMDD

abnormal ductus venosus topology ( J:239583 )

DMDD

abnormal ductus venosus valve topology ( J:239583 )

DMDD

absent ductus venosus valve ( J:239583 )

DMDD

ductus venosus stenosis ( J:239583 )

DMDD

abnormal hepatic vein morphology ( J:239583 )

DMDD

left sided inferior vena cava ( J:239583 )

DMDD

absent intrahepatic inferior vena cava segment ( J:239583 )

DMDD

dual inferior vena cava ( J:239583 )

DMDD

abnormal pectinate muscle morphology ( J:239583 )

DMDD

abnormal atrioventricular cushion morphology ( J:239583 )

DMDD

double outlet left ventricle ( J:239583 )

DMDD

double outlet right ventricle ( J:239583 )

DMDD

transposition of great arteries ( J:239583 )

DMDD

anomalous pulmonary venous connection ( J:239583 )

DMDD

abnormal mitral valve cusp morphology ( J:239583 )

DMDD

double inlet heart left ventricle ( J:239583 )

DMDD

abnormal interatrial septum morphology ( J:239583 )

DMDD

common atrium ( J:239583 )

DMDD

abnormal heart position or orientation ( J:239583 )

DMDD

perimembraneous ventricular septal defect ( J:239583 )

DMDD

muscular ventricular septal defect ( J:239583 )

DMDD

bicuspid pulmonary valve ( J:239583 )

DMDD

craniofacial

persistent right 6th pharyngeal arch artery ( J:239583 )

DMDD

abnormal incisor morphology ( J:239583 )

DMDD

absent upper incisors ( J:239583 )

DMDD

abnormal maxilla morphology ( J:239583 )

DMDD

abnormal tongue epithelium morphology ( J:239583 )

DMDD

short tongue ( J:239583 )

DMDD

abnormal nasal septum morphology ( J:239583 )

DMDD

digestive/alimentary system

abnormal tongue epithelium morphology ( J:239583 )

DMDD

short tongue ( J:239583 )

DMDD

abnormal intestine placement ( J:239583 )

DMDD

intestinal/bowel diverticulum ( J:239583 )

DMDD

embryo

persistent right 6th pharyngeal arch artery ( J:239583 )

DMDD

abnormal umbilical vein topology ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal Mullerian duct morphology ( J:239583 )

DMDD

abnormal Wolffian duct connection ( J:239583 )

DMDD

embryo cyst ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal adrenal gland morphology ( J:239583 )

DMDD

abnormal adenohypophysis morphology ( J:239583 )

DMDD

absent adenohypophysis ( J:239583 )

DMDD

abnormal neurohypophysis morphology ( J:239583 )

DMDD

abnormal thymus topology ( J:239583 )

DMDD

abnormal pancreas morphology ( J:239583 )

DMDD

small pancreas ( J:239583 )

DMDD

abnormal ovary morphology ( J:239583 )

DMDD

ectopic ovary ( J:239583 )

DMDD

growth/size/body

abnormal incisor morphology ( J:239583 )

DMDD

absent upper incisors ( J:239583 )

DMDD

abnormal tongue epithelium morphology ( J:239583 )

DMDD

short tongue ( J:239583 )

DMDD

abnormal nasal septum morphology ( J:239583 )

DMDD

embryo cyst ( J:239583 )

DMDD

thoracoschisis ( J:239583 )

DMDD

heterotaxia ( J:239583 )

DMDD

abdominal situs ambiguus ( J:239583 )

DMDD

left pulmonary isomerism ( J:239583 )

DMDD

hematopoietic system

abnormal thymus topology ( J:239583 )

DMDD

small spleen ( J:239583 )

DMDD

accessory spleen ( J:239583 )

DMDD

homeostasis/metabolism

subcutaneous edema ( J:239583 )

DMDD

immune system

abnormal thymus topology ( J:239583 )

DMDD

small spleen ( J:239583 )

DMDD

accessory spleen ( J:239583 )

DMDD

enlarged lymphatic vessel ( J:239583 )

DMDD

blood in lymph vessels ( J:239583 )

DMDD

integument

subcutaneous edema ( J:239583 )

DMDD

limbs/digits/tail

polydactyly ( J:239583 )

DMDD

liver/biliary system

abnormal liver morphology ( J:239583 )

DMDD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

muscle

abnormal pectinate muscle morphology ( J:239583 )

DMDD

abnormal eye muscle morphology ( J:239583 )

DMDD

abnormal diaphragm morphology ( J:239583 )

DMDD

abnormal infrahyoid muscle connection ( J:239583 )

DMDD

neoplasm

increased hemangioma incidence ( J:239583 )

DMDD

embryo tumor ( J:239583 )

DMDD

nervous system

small superior cervical ganglion ( J:239583 )

DMDD

reduced sympathetic cervical ganglion size ( J:239583 )

DMDD

abnormal brain morphology ( J:239583 )

DMDD

abnormal brain vasculature morphology ( J:239583 )

DMDD

anastomosis between internal carotid artery and basilar artery ( J:239583 )

DMDD

absent segment of anterior cerebral artery ( J:239583 )

DMDD

absent segment of posterior cerebral artery ( J:239583 )

DMDD

enlarged brain ventricles ( J:239583 )

DMDD

abnormal choroid plexus morphology ( J:239583 )

DMDD

abnormal brain internal capsule morphology ( J:239583 )

DMDD

abnormal forebrain morphology ( J:239583 )

DMDD

abnormal adenohypophysis morphology ( J:239583 )

DMDD

absent adenohypophysis ( J:239583 )

DMDD

abnormal neurohypophysis morphology ( J:239583 )

DMDD

abnormal olfactory bulb morphology ( J:239583 )

DMDD

abnormal hindbrain morphology ( J:239583 )

DMDD

small superior vagus ganglion ( J:239583 )

DMDD

abnormal hypoglossal nerve topology ( J:239583 )

DMDD

absent oculomotor nerve ( J:239583 )

DMDD

thin oculomotor nerve ( J:239583 )

DMDD

abnormal optic chiasm morphology ( J:239583 )

DMDD

thin motoric part of trigeminal nerve ( J:239583 )

DMDD

abnormal intrathoracic topology of vagus nerve ( J:239583 )

DMDD

abnormal spinal cord morphology ( J:239583 )

DMDD

renal/urinary system

bifid ureter ( J:239583 )

DMDD

double ureter ( J:239583 )

DMDD

reproductive system

abnormal ovary morphology ( J:239583 )

DMDD

ectopic ovary ( J:239583 )

DMDD

respiratory system

abnormal nasal septum morphology ( J:239583 )

DMDD

left pulmonary isomerism ( J:239583 )

DMDD

abnormal infrahyoid muscle connection ( J:239583 )

DMDD

skeleton

abnormal incisor morphology ( J:239583 )

DMDD

absent upper incisors ( J:239583 )

DMDD

abnormal maxilla morphology ( J:239583 )

DMDD

abnormal rib morphology ( J:239583 )

DMDD

abnormal vertebral arch morphology ( J:239583 )

DMDD

fusion of vertebral arches ( J:239583 )

DMDD

abnormal vertebral body morphology ( J:239583 )

DMDD

vision/eye

abnormal eye muscle morphology ( J:239583 )

DMDD

abnormal optic chiasm morphology ( J:239583 )

DMDD

aphakia ( J:239583 )

DMDD

abnormal optic cup morphology ( J:239583 )

DMDD

abnormal optic stalk morphology ( J:239583 )

DMDD