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Phenotypes Associated with This Genotype
Genotype
MGI:5617222
Allelic
Composition		 Ifih1Rgsc422/Ifih1+
Ifnar1tm1Agt/Ifnar1+
Genetic
Background		 involves: 129S2/SvPas * C57BL/6JJcl * DBA/2JJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ifih1Rgsc422 mutation (0 available); any Ifih1 mutation (50 available)
Ifnar1tm1Agt mutation (13 available); any Ifnar1 mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
glomerulonephritis ( J:209917 )
• less severe than in mice wild-type for Ifnar1

renal/urinary system
glomerulonephritis ( J:209917 )
• less severe than in mice wild-type for Ifnar1

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory