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Phenotypes Associated with This Genotype
Genotype
MGI:5615722
Allelic
Composition		 Rad21ltm1Yow/Rad21ltm1Yow
Rec8mei8/Rec8mei8
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rad21ltm1Yow mutation (1 available); any Rad21l mutation (34 available)
Rec8mei8 mutation (1 available); any Rec8 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal meiosis ( J:209347 )
• males and females do not form either cohesion axes or chromosome axes
abnormal male meiosis ( J:209347 )
• spermatocytes exhibit enhanced bouquet arrest

cellular
abnormal meiosis ( J:209347 )
• males and females do not form either cohesion axes or chromosome axes
abnormal male meiosis ( J:209347 )
• spermatocytes exhibit enhanced bouquet arrest

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory