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Phenotypes Associated with This Genotype
Genotype
MGI:5615606
Allelic
Composition		 Cd209dtm1.1Cfg/Cd209dtm1.1Cfg
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd209dtm1.1Cfg mutation (1 available); any Cd209d mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased B cell proliferation ( J:217719 )
• following anti-IgM stimulation
increased B cell number ( J:217719 )
• IgG+ IgM+ B cells in the spleen
• slight increase in B220+ CD22+ cells

adipose tissue
abnormal fat cell morphology ( J:217719 )
• increased adipocyte numbers in the bone marrow at 12 weeks and 1 year of age

hematopoietic system
increased B cell proliferation ( J:217719 )
• following anti-IgM stimulation
increased B cell number ( J:217719 )
• IgG+ IgM+ B cells in the spleen
• slight increase in B220+ CD22+ cells

cellular
increased B cell proliferation ( J:217719 )
• following anti-IgM stimulation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory