Phenotypes Associated with This Genotype

Genotype
MGI:5614812

• Allelic Composition: Tg(SULT1A1,SULT1A2)1Glatt/0
• Genetic Background: FVB/N-Tg(SULT1A1,SULT1A2)1Glatt

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal cell physiology ( J:217578 )

• mice treated with 1-methylpyrene exhibit an increase in benzylic DNA adducts in the liver, lung, heart and kidney, but not colon, compared with wild-type mice

homeostasis/metabolism

abnormal blood homeostasis ( J:217578 )

• mice treated with 1-methylpyrene exhibit increased electrophilic 1-sulfooxymethylpyrene plasma levels compared with wild-type mice