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Phenotypes Associated with This Genotype
Genotype
MGI:5614646
Allelic
Composition		 Aars1sti/Aars1tm1.1Slac
Genetic
Background		 involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aars1sti mutation (1 available); any Aars1 mutation (68 available)
Aars1tm1.1Slac mutation (0 available); any Aars1 mutation (68 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal myocardial fiber morphology ( J:216802 )
• ubiquitin and p62-positive puncta are seen in cardiomyocytes
cardiac fibrosis ( J:216802 )
• widespread myocardial fibrosis at 4 months of age

growth/size/body
decreased body size ( J:216802 )
• small body size

integument
alopecia ( J:216802 )
• dorsal alopecia

muscle
abnormal myocardial fiber morphology ( J:216802 )
• ubiquitin and p62-positive puncta are seen in cardiomyocytes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory