About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5614091
Allelic
Composition		 Rb1tm1Tyj/Rb1+
Genetic
Background		 involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rb1tm1Tyj mutation (5 available); any Rb1 mutation (117 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:215358 )
• mice develop pituitary gland tumors with a mean survival of 400 days

neoplasm
increased pituitary gland tumor incidence ( J:215358 )
• mice develop pituitary gland tumors with a mean survival of 400 days

endocrine/exocrine glands
increased pituitary gland tumor incidence ( J:215358 )
• mice develop pituitary gland tumors with a mean survival of 400 days

nervous system
increased pituitary gland tumor incidence ( J:215358 )
• mice develop pituitary gland tumors with a mean survival of 400 days

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory