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Phenotypes Associated with This Genotype
Genotype
MGI:5614080
Allelic
Composition		 Rad50tm4.1Jpt/Rad50+
Spo11tm1Mjn/Spo11tm1Mjn
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rad50tm4.1Jpt mutation (0 available); any Rad50 mutation (53 available)
Spo11tm1Mjn mutation (2 available); any Spo11 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal seminiferous tubule morphology ( J:209141 )
• severely reduced cellularity

endocrine/exocrine glands
abnormal seminiferous tubule morphology ( J:209141 )
• severely reduced cellularity

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory